It penetrates through the blood-barrier. Systemic absorption during installation in the conjunctival sac – small. When liothyronine side effects instilled in the conjunctival sac in therapeutic concentrations detected in the corneal stroma, moisture anterior chamber, vitreous body for 6 hours. Aminoglycosides are not metabolized, excreted by the kidneys.
Indications Infections of the eye and its appendages: blepharitis, conjunctivitis, keratoconjunctivitis, Blepharoconjunctivitis, keratitis, endophthalmitis, dacryocystitis, meybomit (barley). Prevention of postoperative infectious complications in ophthalmology.
Contraindications : Hypersensitivity to the drug, age under 18 years, pregnancy, lactation.
Dosing and Administration Locally. 1 drop every 4 h; in acute liothyronine side effects infections can be repeated instillation every 30 minutes or 1 hour. In non-severe course of infection, the drug is instilled 1-2 drops into the conjunctival sac of the affected eye (or eyes) every 4 hours. In the case of severe acute infection (endophthalmitis) drug liothyronine sod side effects instilled every 30-60 minutes decreasing inflammation installations reduce the frequency of the drug.
Side effects: In applying the drug may be a manifestation of allergic reactions in 15% of cases: burning, crawling, itching of the conjunctiva; 1-5%: mucosal hyperemia eye, foreign body sensation in the eye, excessive tearing, less than 1%: blepharitis, keratitis, swelling eyelids, eye pain, chemosis, crystal deposition, corneal ulceration.
Cautions Intended only for local liothyronine side effects use. The vial must be closed after each use. Do not touch the eye pipette tip to maintain sterility of the solution. Long-term use of the as in the case of other antibiotics can lead to enhanced growth of microorganisms refractory (including fungi). It is recommended to do seeding after treatment if clinical outcome is unsatisfactory. Patients using hard contact lenses should apply eye drops only after removal of contact lenses. The lenses can be worn 15 minutes after instillation of the drug. In the period of treatment can not wear soft contact lenses. With the development of allergic reactions, use of the drug liothyronine t3 should be discontinued. Before applying the contents of the vial should be shaken.
Effects on ability to drive vehicles and working with special equipment preparation Application does not cause fatigue and visual impairment, therefore, does not affect the ability to drive vehicles and management mechanisms. Patients who have temporarily lost after the application of clarity, it is not recommended to drive or operate complex machinery immediately after instillation of the drug.
Overdose Symptoms: punctate keratitis, erythema, increased lacrimation, itching, and swelling of the century. Treatment: symptomatic therapy.
Interaction with other medicinal products In the case of co-administration of the with systemic antibiotics of the aminoglycoside may increase liothyronine side effects systemic side effects (nephrotoxicity, ototoxicity action, violation of mineral metabolism and hematopoiesis).